Cyclic Leukocyte Oscillations in Chronic Myelogenous Leukemia During Hydroxyurea Therapy
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چکیده
منابع مشابه
Cyclic leukocyte oscillations in chronic myelogenous leukemia during hydroxyurea therapy.
By B. J. KENNEDY T HE SUCCESSFUL TREATMENT of cancer and leukemia by agents which have hematosuppressive effects depends upon a selective toxicity, whereby the tumor cell is inhibited rather than the normal cell. Further information is needed on the life of the leukocyte, particularly the generative cycle and the normal or abnormal physiologic rhythms. The basic mechanism of the movement of leu...
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Studies were performed on a teen-age female identical twin with cyclic leukocytosis and Ph’-positive chronic myelogenous leukemia (CML), in an attempt to analyze the relationship of these cycles to her disease and to utilize the cycles as reference points for kinetic studies and as landmarks in the progression of her disease. She remained untreated for 2V2 yr. Colony-stimulating factor levels s...
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(IFN-␣) can induce molecular remission in chronic myelogeneous leukemia (CML). 1 This may indicate that it could be opportune to prolong IFN treatment for a long time; however, albeit rarely, this therapeutic strategy can produce unusual complications. 2 In this regard, we believe it useful to report the development of pericardial effusion in a 28-year-old Ph-positive CML patient during therapy...
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ژورنال
عنوان ژورنال: Blood
سال: 1970
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v35.6.751.751